This textbook presents more than 250 current problems from modern biophysics and related fields of application, together with detailed solutions. The problems emphasize concepts and information that are essential for an understanding of the fundamental physical processes in life sciences, including medical science. The book is divided into 11 chapters and the topics follow the sequence of dimensions and diversity of the living world. It starts with the basic principles relating to the energetics of the living world, and moves on to problems from the microworld (biophysics of molecules and membranes) and the macroworld (biomechanics, biophysics of organs, radiation and the environment).